: any of various largely nocturnal mice (genus Peromyscus) of North and Central America typically having whitish feet and underparts
especially: a common woodland mouse (P. leucopus) of North America
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The best predictor of how many ticks are likely to be around each year is how many white-footed mice were present the previous summer, Ostfeld told CNN.—
Meg Tirrell,
CNN Money,
14 July 2026 For Lyme disease, deer feed the adult ticks that carry the bacterium but do not transmit it themselves; the spirochete is maintained by small mammals and birds, especially white-footed mice.—
John Drake,
Forbes.com,
4 July 2026 Hantavirus is an infectious disease that's normally spread through contact with rodents such as deer mice, cotton rats, rice rats and the white-footed mouse.—
Gina Kalsi,
PEOPLE,
22 June 2026 The virus is primarily carried by wild rodents, such as deer mice and white-footed mice.—
Alyssa Goldberg,
USA Today,
18 May 2026 See All Example Sentences for white-footed mouse
: a common woodland mouse (Peromyscus leucopus) that has whitish feet and underparts and that is a reservoir for the spirochete of the genus Borrelia (B. burgdorferi) causing Lyme disease